Nucleic Acid Molecular Weight Calculator
Calculate the molecular weight of a nucleic acid based on its sequence.
Supports adjustable parameters such as 5' end modifications (hydroxyl, phosphate) and nucleic acid shape (linear or circular).
Ideal for accurate mass calculations in molecular biology experiments and nucleic acid design.
What is the Nucleic Acid Molecular Weight Calculator?
This tool calculates the precise molecular weight of a nucleic acid based on its sequence. It supports multiple adjustable parameters to accommodate different experimental designs and molecular types.
Core Functionalities
- Sequence-Based MW Calculation:
Input the nucleic acid sequence to calculate the exact molecular weight. - Supported Nucleic Acid Types:
Double-stranded DNA (dsDNA), single-stranded DNA (ssDNA), single-stranded RNA (ssRNA). - Adjustable Parameters:
Choose 5' end modifications (hydroxyl, phosphate) and nucleic acid shape (linear or circular). - Rich Output:
The tool provides molecular weight, GC%, sequence composition analysis, and molecular weight composition charts.
Nucleotide Molecular Weight Table
A = 313.2 g/mol
T = 304.2 g/mol
C = 289.2 g/mol
G = 329.2 g/mol
For ssRNA:
A = 329.2 g/mol
C = 305.2 g/mol
G = 345.2 g/mol
U = 306.2 g/mol
Experimental Applications
This molecular weight calculator helps design nucleic acid experiments, predict solution concentrations, and analyze sequence compositions. Accurate molecular weight calculation is essential for qPCR, cloning, in vitro transcription, and nucleic acid labeling workflows.
